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(Online CE Course)

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Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 2 hour(s)
Course number 578-024-20, approved through 3/31/2022
Florida Board of Clinical Laboratory Personnel Credit Hours - General (Clinical Chemistry/UA/Toxicology): 2 hour(s)
Course number 20-695581, approved through 9/1/2020


  • Recall the basic biochemistry of the thyroid hormones.
  • Describe the basic feedback mechanism between the thyroid and pituitary.
  • Identify the classic symptoms of hypothyroidism and hyperthyroidism.
  • List the assays used to assess thyroid function.
  • Explain the role of the laboratory in determining the effectiveness of thyroid treatments.

Course Outline

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  • Introduction
  • Thyroid Anatomy and Histology
      • Overview of the Anatomy of the Thyroid Gland
    • Thyroid Gland: Location
      • Locating the Thyroid Gland
    • Thyroid Gland: Structure
    • Thyroid Gland: Histological Features
      • Histological Features of the Thyroid Gland
  • Thyroid Function
  • Biochemistry of Thyroid Hormones
      • The Biochemistry of Thyroid Hormones
      • Thyroid Biochemistry: Summary
    • Thyroxine (T4)
      • Assembly of the T4 Molecule
    • Triiodothyronine (T3)
      • Assembly of the T3 Molecule
    • Total and Free Forms of T3 and T4
  • Endocrinological Relationships
  • Disorders of the Thyroid Gland
      • Disorders of the Thyroid Gland
    • Euthyroid - Definition
    • Hypothyroidism
      • Hypothyroidism: Symptoms and Clinical Features
      • Hypothyroidism: Primary Versus Secondary
      • Hypothyroidism: Subclinical
      • Hypothyroidism: Incidence and Risk
      • Hypothyroidism: Laboratory Findings
      • Hypothyroidism: Treatment and Monitoring
      • Which of the following would be considered among the classic symptoms of hypothyroidism?
    • Hyperthyroidism
      • Hyperthyroidism: Clinical Symptoms
      • Hyperthyroidism: Primary Versus Secondary
      • Hyperthyroidism: Incidence and Risk
      • Hyperthyroidism: Laboratory Findings
      • Why would an excessive production of thyroid hormone cause the level of TSH to be low?
    • Autoimmune Disorders of the Thyroid
    • Neoplasma and Malignant Conditions
  • Laboratory Analysis of Thyroid Markers
      • Analytical Methods for Thyroid Hormone Measurement
    • TSH
    • Hormones Produced by the Thyroid Gland
      • Analysis of T4 and Free T4 (FT4)
      • Analysis of T3 and Free T3 (FT3)
    • Reverse T3
    • T-Uptake
      • Historical Assessment of T-Uptake
    • Free Thyroxine Index
      • Historical Estimation of the Free Thyroxine Index (FTI)
    • Thyroglobulin
    • Thyroglobulin Antibody (TgAb)
      • Analysis of Thyroglobulin Antibody (TgAb)
    • Thyroperoxidase Antibody (TPOAb)
      • Analysis of Thyroperoxidase Antibody (TPOAb)
      • The sensitivity of thyroid function testing has improved through the development of immunoassay methods with enhanced detection capabilities.
  • Clinical Case Studies
    • Clinical Case Study #1
      • Primary Hypothyroidism: Case Report
    • Clinical Case Study #2
      • Secondary Hyperthyroidism: Case Report
  • References
      • References
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