References

How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 183 CE courses, most popular
$109Add to cart
Pick Your Courses
Up to 8 CE hours
$55Add to cart
Individual course$25Add to cart
The page below is a sample from the LabCE course HLA and Cancer Immunotherapy. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about HLA and Cancer Immunotherapy (online CE course)
References

Actor JK. Chapter 4 - T Lymphocytes: Ringleaders of adaptive immune function. In: Introductory Immunology: Basic Concepts for Interdisciplinary Applications. 3rd ed. Academic Press. February 2023.
Alger S. Scientists discover how immune cells survive their battle with cancer. Press release. Massachusetts General Hospital, August 10, 2021. Accessed August 9, 2023. https://www.massgeneral.org/news/press-release/scientists-discover-how-immune-cells-survive-their-battle-with-cancer-2
American Association for Cancer Research (AACR). He had metastatic melanoma, recently said he was cancer-free after treatment with Pembrolizumab. No date. Accessed August 8, 2023. https://www.aacr.org/patients-caregivers/progress-against-cancer/jimmy-carter/
Ayob AZ, Ramasamy TS. Cancer stem cells as key drivers of tumour progression. J Biomed Sci. 2018;25(1):20. Published 2018 Mar 6. doi:10.1186/s12929-018-0426-4
Babay W, Boujelbene N, Ben Yahia H, et al. Prognostic significance of high circulating sHLA-G in ovarian carcinoma. HLA. 2021;98(4):357-365. doi:10.1111/tan.14374
Brea EJ, Oh CY, Manchado E, et al. Kinase regulation of human MHC Class I molecule expression on cancer cells. Cancer Immunol Res. 2016;4(11):936-947. doi:10.1158/2326-6066.CIR-16-0177
Cruz-Tapias P, Castiblanco J, Anaya JM. Major histocompatibility complex: Antigen processing and presentation. In: Anaya JM, Shoenfeld Y, Rojas-Villarraga A, et al., editors. Autoimmunity: From Bench to Bedside [Internet]. Bogota (Colombia): El Rosario University Press; 2013 Jul 18. Chapter 10. Accessed August 8, 2023. https://www.ncbi.nlm.nih.gov/books/NBK459467/
Di Tomaso T, Mazzoleni S, Wang E, et al. Immunobiological characterization of cancer stem cells isolated from glioblastoma patients. Clin Cancer Res. 2010;16(3):800-813. doi:10.1158/1078-0432.CCR-09-2730
Hazini A, Fisher K, Seymour L. Deregulation of HLA-I in cancer and its central importance for immunotherapy. J Immunother Cancer. 2021;9(8):e002899. doi:10.1136/jitc-2021-002899
JAMA Network Editors. AMA Manual of Style - A Guide for Authors and Editors. 11th ed. Oxford University Press. 2020.
Marsh SGE, Albert ED, Bodmer WF, et al. Nomenclature for factors of the HLA system, 2010. Tissue Antigens 2010;75:291-455. doi: 10.1111/j.1399-0039.2010.01466.x; Accessed August 8, 2023. https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1399-0039.2010.01466.x
Naranbhai V, Viard M, Dean M, et al. HLA-A*03 and response to immune checkpoint blockade in cancer: an epidemiological biomarker study. Lancet Oncol. 2022;23(1):172-184. doi:10.1016/S1470-2045(21)00582-9
Pietra G, Manzini C, Vitale M, et al. Natural killer cells kill human melanoma cells with characteristics of cancer stem cells. Int Immunol. 2009;21(7):793-801. doi:10.1093/intimm/dxp047
Press release. NobelPrize.org. Nobel Prize Outreach AB. October 1, 2018. Accessed August 8, 2023. https://www.nobelprize.org/prizes/medicine/2018/press-release/
Ran GH, Lin YQ, Tian L, et al. Natural killer cell homing and trafficking in tissues and tumors: from biology to application. Signal Transduct Target Ther. 2022;7(1):205. Published 2022 Jun 29. doi:10.1038/s41392-022-01058-z
Schaafsma E, Fugle CM, Wang X, Cheng C. Pan-cancer association of HLA gene expression with cancer prognosis and immunotherapy efficacy. Br J Cancer. 2021;125(3):422-432. doi:10.1038/s41416-021-01400-2
Sommer S. The importance of immune gene variability (MHC) in evolutionary ecology and conservation. Front Zool. 2005;2:16. Published 2005 Oct 20. doi:10.1186/1742-9994-2-16
Speed read: Seeking signs of compatibility. NobelPrize.org. Nobel Prize Outreach. Accessed August 8, 2023. https://www.nobelprize.org/prizes/medicine/1980/speedread/
Volonté A, Di Tomaso T, Spinelli M, et al. Cancer-initiating cells from colorectal cancer patients escape from T cell-mediated immunosurveillance in vitro through membrane-bound IL-4. J Immunol. 2014;192(1):523-532. doi:10.4049/jimmunol.1301342
Watson S. Types of immunotherapy. WebMD. January 11, 2021. Accessed August 9, 2023. https://www.webmd.com/cancer/immunotherapy-treatment-types#1-4
Yeung JT, Hamilton RL, Ohnishi K, et al. LOH in the HLA class I region at 6p21 is associated with shorter survival in newly diagnosed adult glioblastoma. Clin Cancer Res. 2013;19(7):1816-1826. doi:10.1158/1078-0432.CCR-12-2861
Zamora AE, Crawford JC, Thomas PG. Hitting the target: How T cells detect and eliminate tumors. J Immunol. 2018;200(2):392-399. doi:10.4049/jimmunol.1701413
Note: All images (figures 1-5) used throughout this module were created by the author, Dr. Nancy Liu-Sullivan.