According to CLSI M45, multiple coryneform-type organisms can be tested using the same inoculation, incubation, and interpretations as Corynebacterium species. Organisms that are considered to be coryneform for the purpose of susceptibility testing include the following: Archanobacter, Arthrobacter, Brevibacterium, Cellulomonas, Cellulosimicrobium, Dermabacter, Leifsonia, Microbacterium, Oerskovia, Rothia (excluding Rothia mucilaginosa), Trueperella, and Turicella.
Currently, other species do not have enough data available to support using these susceptibility protocols and interpretations of results. These include: Auritidibacter, Curtobacterium, Exiguobacterium, Helcobacillus, Janibacter, Knoellia, and Pseudoclavibacter.
In addition, there are other gram-positive bacilli that have been shown to have reliable test results using these test methods and while they are not considered coryneform, the methods and interpretations for susceptibility testing may be used for the following organisms: aerobic Actinomyces (A. bovis, A. europaeus, A. graevenitzii, A. johnsonii, A. naeslundii, A. neuii, A. odonotolyticus, A. oris group, A. radingae, A. turicensis, A. urogenitalis, A. viscosus), aerobic Bifidobacterium (B. scardovii and B. tsurumense), and some Varibaculum species. Other strains of these genera should be tested using the anaerobic method.
