HIV Introduction and Structure

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The page below is a sample from the LabCE course HIV: Structure, Replication, and Detection. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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HIV Introduction and Structure

The Human Immunodeficiency Virus (HIV) belongs to the Family Retroviridae, RNA retroviruses that use the enzyme reverse transcriptase to convert viral RNA into DNA. There are two forms of HIV that are associated with human disease. HIV-1 is the most prevalent form worldwide. HIV-2 makes up less than 10% of cases and is found almost exclusively in West Africa.
Both forms of HIV consist of a core of ribonucleic acid (RNA) called the genome, a protein component that surrounds the genome called a capsid, and a lipid bilayer envelope that surrounds them both.
1. National Institute of Health. “The HIV Life Cycle.” National Institutes of Health, 4 Aug. 2021, https://hivinfo.nih.gov/understanding-hiv/fact-sheets/hiv-life-cycle.

HIV Virus. (1)