Whole blood methods that detected platelet aggregation using electrical impedance technology can also be utilized for clopidogrel response testing. In one method, ADP is used as the agonist, typically at a concentration of 5-20 µmol/L. If a patient's test result shows a low response (ADP-induced impedance exceeding 5 Ω (ohms)), it could indicate clopidogrel non-responsiveness.