Aluminum

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The page below is a sample from the LabCE course Introduction to Trace Elements and Heavy Metals. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Aluminum

Aluminum is the third most common element in the Earth's crust. Thus, it is naturally found in air, soil, and water. Aluminum has been deemed 'GRAS' by the FDA, an acronym for "Generally Recognized as Safe." However, studies on environmental poisoning have shown that aluminum can be a threat to humans and animals.
Aluminum products are widely used by humans and industries. Aluminum can be found in drinking water, food, air, medicine, deodorants, cosmetics, and most industrial settings. Some antacids also contain aluminum salts.
When present in high concentrations, aluminum can elicit oxidative stress in the brain, liver, and kidneys. Aluminum may disrupt or inhibit several enzymes and alter protein synthesis, nucleic acid function, and cell membrane permeability. It also appears to affect plasma levels of triglycerides and their metabolism in the body.
Absorption:
About 5-10 mg of aluminum is estimated to be ingested daily. In healthy persons, this amount can be easily secreted by the kidneys. Depending on the form or salt of aluminum present, 0.1-5% of ingested aluminum is absorbed.