Many hormones are affected by sleep deprivation and disruption of the circadian rhythms, including thyroid stimulating hormone (TSH) and thyroxine (T4).
Studies have found that sleep deprivation is associated with higher white blood cell (WBC) counts and absolute neutrophil counts, as well as significantly shorter hemostasis parameters, including prothrombin time (PT) and thrombin time (TT).
The lack of restorative sleep results in an increase in stress as well.