The CDC coordinates national surveillance for diseases and conditions in the National Notifiable Diseases Surveillance System (NNDSS)10 which includes but is not limited to, measles, mumps, rubella, congenital rubella syndrome, diphtheria, tetanus, pertussis, poliovirus infection (nonparalytic), paralytic poliomyelitis, Haemophilus influenzae invasive disease, invasive pneumococcal disease (IPD), meningococcal disease, hepatitis A, hepatitis B, novel influenza A virus infections, influenza-associated pediatric mortality, and varicella.
The reporting is done through state and local public health officials and requirements for reporting are mandated by state laws and regulations. It is anticipated that the reporting will be enhanced by linking electronic case notifications with electronic clinical and laboratory data.
Keep in mind that not every "reportable" disease is a vaccine-preventable disease. For example, syphilis and gonorrhea are reportable diseases because they are important to keep track of for public health monitoring. However, we do not have vaccines for them so they are not vaccine-preventable diseases.