The table describes some of the more common autoimmune diseases:
Autoimmune Disease | Description |
Rheumatoid arthritis (RA) | Inflammation of joints and surrounding tissues caused by autoantibodies and immune complex deposition |
Systemic lupus erythematosus (SLE) | A systemic disorder that affects skin, joints, kidneys, brain, and other organs |
Celiac sprue disease | Reaction to gluten (found in wheat, rye, and barley) that causes damage to the lining of the small intestine |
Pernicious anemia (PA) | Decrease in red blood cells due to inability to absorb vitamin B12 which is caused by autoantibodies to intrinsic factor and intrinsic factor-secreting gastric parietal cells
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Vitiligo | Melanocytes are attacked and destroyed leading to white patches on the skin caused from the loss of pigment |
Scleroderma | Connective tissue disease that causes changes in the skin, blood vessels, muscles, and internal organs |
Psoriasis | Autoimmune skin condition that causes redness and irritation, as well as thick, flaky, silver-white patches |
Inflammatory bowel diseases (IBD) | Group of inflammatory diseases of the colon and small intestine |
Hashimoto's disease | Inflammation of the thyroid gland leading to hypothyroidism |
Addison's disease | Immune destruction of adrenal glands causing adrenal hormone insufficiency |
Graves' disease | Overactive thyroid gland triggered by autoantibodies |
Reactive arthritis | Inflammation of the joints, urethra, and eyes; may cause lesion on the skin and mucous membranes |
Sjögren's syndrome (SjS) | Destroys glands that produce tears and saliva causing dry eyes/mouth; may affect kidneys and lungs |
Type 1 diabetes | Destruction of insulin-producing cells in the pancreas |