Table 2: Heparin vs. Warfarin Summary Chart - LabCE.com, Laboratory Continuing Education

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Table 2: Heparin vs. Warfarin Summary Chart

	Heparin	Warfarin
How fast does it work?	Within minutes	Days later
How is it given?	Injected	By mouth
Where does it work?	In the blood	In the liver
How does it work?	Enhances ATIII activity, increases inhibition of thrombin (factor IIa)	Prevents Vitamin K from modifying factors II, VII, IX, and X to their active form
Lab monitoring?	aPTT, with goal aPTT 1.5 - 2.5X reference range	INR (PT) with goal INR of 2-3
Antidote in toxicity?	Protamine	Vitamin K
How long is it used?	For a shorter period of time	Long term
Safe in pregnancy?	Yes	No