Malassezia species are commensals of the skin. Some species are lipid-dependent. Tinea versicolor is a common infection of the superficial epidermis caused by Malassezia spp. It is one of the most common cutaneous infections worldwide in the tropics and subtropics. Malassezia spp. may rarely cause bloodstream infections; these are usually associated with an indwelling intravascular catheter and the administration of hyperalimentation that contains lipids.
The organisms appear as microscopic yeasts about 2 µm in diameter with unipolar broad-based budding. Budding yeasts resemble bowling pins, while the daughter cell budding from the parent cell is sometimes likened to a turtle head coming out of its shell.
Note: If infection by Malassezia spp. is suspected, it is important to notify the laboratory so that long-chain fatty acid supplements (olive oil or Tween) can be added to culture media.
The image to the right is Malassezia furfur, demonstrating yeast-like fungal cells and short hyphal elements.
13. CDC/Georg. (1964). Image #2916. This photomicrograph of a skin-scale tissue sample reveals the presence of numerous Malassezia furfur fungal organisms. Usually, M. furfur grows sparsely without causing a rash. In some individuals, it grows more actively for reasons unknown, resulting in pale brown flaky patches on the trunk, neck, or arms. PHIL public domain. https://phil.cdc.gov/Details.aspx?pid=2916 14. CDC/ Georg. (1964). Image #3938. This photomicrograph of a skin scale tissue specimen revealed some of the ultrastructural characteristics found in a case of tinea versicolor, produced by the fungal organismMalassezia furfur, which included yeast-like fungal cellsand short hyphal elements. PHIL public domain. https://phil.cdc.gov/Details.aspx?pid=3938
