Anisocytosis Reference Table

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The page below is a sample from the LabCE course Red Cell Disorders: Peripheral Blood Clues to Nonneoplastic Conditions. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Anisocytosis Reference Table

Cell TypeImageCellular DescriptionAssociated Diseases and Conditions
  • MCV 80-100 fL (approximately the same size as the nucleus of a small lymphocyte)
  • MCHC 32-36 g/dL or 32%-36%
  • N/A; cell is normal
  • Red blood cells are smaller than normal
  • MCV < 80 fL
  • Iron deficiency anemia
  • Sideroblastic anemia
  • Certain thalassemias
  • Lead poisoning
  • Certain hemoglobinopathies
  • Red blood cells are larger than normal
  • MCV > 100 fL
  • Megaloblastic Anemia (Vitamin B12/Folate deficiency)
  • Myelodysplasia
  • Liver disease