How Many Calibrators Must Be Analyzed?

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The page below is a sample from the LabCE course Calibration of Clinical Laboratory Analytes. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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How Many Calibrators Must Be Analyzed?

The number of non-zero calibrators required to calibrate an assay depends on the following:
  • Manufacturer recommendations (i.e., product insert specifications)
  • The analytical method
  • The analyte being assayed
The typical number of non-zero calibrators required for a quantitative assay ranges from 1 to 6.