Signs and Symptoms: Brain and Neurological System

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The page below is a sample from the LabCE course Long COVID: Reality to Research. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Signs and Symptoms: Brain and Neurological System

Brain and Neurological System
Brain mass reduction suspected to be the result of inflammation has been reported by British researchers. This physical change represents a greater reduction in gray matter thickness and global brain size with bigger changes in markers of tissue damage in regions connected to the primary olfactory cortex.
Other undesirable outcomes of COVID-19 infections can include an increased risk of developing Parkinson’s and Alzheimer’s disease. In addition, even younger patients can experience strokes, seizures, and Guillain-Barre syndrome, which causes temporary paralysis.
Some individuals develop mid- to long-term symptoms following COVID infection, including brain fog, fatigue, headaches, and dizziness. The cause of these symptoms is unclear at the moment.
However, there is emerging evidence of ACE2 receptors in human brains, indicating the potential brain infection by SARS-CoV-2. Neuroinvasion by SARS-CoV-2 can occur with various possible routes, such as transsynaptic transfer across infected neurons via the olfactory nerve, vascular endothelial cell infection, or migration of leukocytes across the blood-brain barrier.10