Introduction to the 2016 WHO Classification of Myeloid and Lymphoid Neoplasms

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The page below is a sample from the LabCE course Case Studies in Hematology - Malignant WBC Disorders. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Introduction to the 2016 WHO Classification of Myeloid and Lymphoid Neoplasms

The previous reclassification of the myeloid and lymphoid neoplasms took place in 2008. The classification revision in 2016 incorporated new genetic information into morphologic and immunophenotypic characterizations.
The implications of these changes are better diagnostic, prognostic and treatment options.
Not all of the cases in this course deal with the reclassifications, although several do at least incorporate some new criteria and genetic information.
The following two pages will give a very brief summary of the highlights of the changes in the WHO classification system, followed by four cases dealing with familiar and less familiar hematologic malignancies.