Tier 1 biological agents are a subset of select agents and toxins that present the greatest risk of deliberate misuse, with significant potential for mass casualties or devastating effects (on the economy, infrastructure, and public confidence) and a threat to public health and safety.
Tier 1 agents include:
- Bacillus anthracis
- Bacillus cereus Biovar anthracis
- Botulinum neurotoxins
- Botulinum neurotoxin producing strains of Clostridium
- Burkholderia mallei
- Burkholderia pseudomallei
- Ebola virus
- Foot-and-Mouth Disease virus
- Francisella tularensis
- Marburg virus
- Rinderpest virus
- Variola major virus (Smallpox)
- Variola minor virus (Alastrim)
- Yersinia pestis
