Table 3: Hemoglobin Content (MCHC) Classification - LabCE.com, Laboratory Continuing Education

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Table 3: Hemoglobin Content (MCHC) Classification

Cell Type	Image	Cellular Description	Associated Diseases and Conditions
Normochromic		Normal MCH and MCHC (32–36 g/dL or 32–36%) Small central pallor	Normal but can go along with those conditions that are seen with normocytic cells, such as: Hemolytic anemias Hemoglobinopathies Aplastic anemias Leukemias
Hypochromic		MCHC <32 g/dL (or <32%) Red blood cells (RBCs) have a larger than normal central pallor (>3 µ in diameter) due to low hemoglobin content.	Iron deficiency anemia Thalassemias Sideroblastic anemia Lead poisoning Some cases of chronic inflammation
Polychromatophilic		Little or no central pallor Reddish-blue in color Slightly larger than normal RBCs Supravital staining identifies these cells as reticulocytes	Hemorrhage-related conditions Hemolysis Autoimmune hemolytic anemia Newborns Reflective of increased bone marrow compensation