Barbiturates

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The page below is a sample from the LabCE course Drug Testing Methods in the Clinical Toxicology Laboratory. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Barbiturates

Barbiturates are a class of drugs that act as central nervous system depressants. They produce effects ranging from mild sedation to general anesthesia. Short-acting barbiturates have half-lives of 4 to 38 hours, while some longer-acting barbiturates are over 90 hours. Some examples of barbiturates are below. It is worth noting that the drug primidone is metabolized to phenobarbital.
  • Amobarbital
  • Butabarbital
  • Pentobarbital
  • Phenobarbital
  • Primidone
  • Secobarbital
  • Thiopental