TB and LTBI in the United States

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The page below is a sample from the LabCE course Latent Mycobacterium tuberculosis Infection and Laboratory Test Methods. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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TB and LTBI in the United States

TB disease incidence2
The number of TB cases in 2023 was approximately 9, 600 which is an increase of 8.3% compared with 2019. The 2023 case count is the highest reported since 2013.
  • Current incidence rate = 2.9 per 100,000 population
In 2023, the TB case rate was 18.5 times higher among non-US-born individuals compared with US-born individuals.
LTBI prevalence
The number of individuals living with latent TB infection (LTBI) is estimated to be as high as 13 million, according to the Centers for Disease Control and Prevention.
2. CDC releases “Reported Tuberculosis in the United States, 2023.” (2024). Centers for Disease Control and Prevention. https://www.cdc.gov/tb/php/dear-colleague-letters/2024-reported-tuberculosis-2023.html
Figure 5. Division of Tuberculosis Elimination. (2024). Progress towards TB elimination, United States, 1982–2023. Taken from slide set: Tuberculosis (TB) in the United States, 1993–2023. Centers for Disease Control and Prevention. https://www.cdc.gov/tb-surveillance-report-2023/resources/slide-set.html

Figure 5. Progress towards TB elimination in the United States, 1982-2023