Etiology: What is the Cause of Tuberculosis?

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The page below is a sample from the LabCE course Latent Mycobacterium tuberculosis Infection and Laboratory Test Methods. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Etiology: What is the Cause of Tuberculosis?

Tuberculosis (TB) is caused by the bacterial group known as Mycobacterium tuberculosis complex (eg., M. tuberculosis, M. bovis, M. africanum, M. microti, M. canetti, M. pinnipedii, M. mungi, M. caprae). Mycobacterium tuberculosis is the most common of this complex to cause TB disease in humans, while the other members of the complex cause disease similar to TB. These bacteria may be transmitted from person to person through the air. Coughing or sneezing by individuals infected with active TB disease causes the release of microscopic droplets (containing tubercle bacilli) into the air. These droplets may then be inhaled by others. TB usually affects the lungs, but can also cause infection in the brain, spine, kidneys, and other locations. In pulmonary TB, the tubercle bacilli multiply in the alveoli of the lung.
3. CDC/ V. McPheeters. This photomicrograph of a Ziehl-Neelsen-stained specimen revealed the presence of magenta stained, rod-shaped, acid-fast, Mycobacterium tuberculosis bacilli. PHIL. Creation Date: 1965. Copyright Restrictions: None - This image is in the public domain. Accessed March 5, 2022. https://phil.cdc.gov/Details.aspx?pid=23000

This photomicrograph of a Ziehl-Neelsen-stained specimen,
revealed the presence of magenta stained, rod-shaped,
acid-fast, Mycobacterium tuberculosis bacilli. (3)