Crossmatch and Transfusion

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The page below is a sample from the LabCE course Warm Antibodies and Autoantibodies in Blood Banking. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about Warm Antibodies and Autoantibodies in Blood Banking (online CE course)
Crossmatch and Transfusion

Transfusion recommendations can vary by facility. In general, it is recommended to transfuse Rh and Kell negative blood specific to the patient's phenotype as well as antigen negative to any alloantibodies the patient may have. This can be dependent on blood availability and the institution's policies. Because warm autoantibodies will likely interfere with a crossmatch, it may be recommended to transfuse least incompatible, antigen negative blood to the patient.