Testing for Cold Agglutinin Disease in the Blood Bank

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The page below is a sample from the LabCE course Warm Antibodies and Autoantibodies in Blood Banking. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Testing for Cold Agglutinin Disease in the Blood Bank

Most cold autoantibodies discovered in the blood bank are clinically insignificant. However, if the autoantibody has a high titer and high thermal amplitude, the patient should be evaluated for cold agglutinin disease.