Cardiac biomarkers are essential tools for patient care. Interrupted or blocked blood flow and decreased oxygen cause injury to the myocytes and eventually cell death. As the myocytes become necrotic, their membranes are disrupted and intracellular biomolecules diffuse into the cardiac microvasculature. These compounds, many of which are biomarkers that can be measured, then enter the peripheral circulation.
Cardiac biomarkers are relied upon for the detection and monitoring of two categories of cardiovascular disease:
- Acute ischemic disease (an acute myocardial infarction (AMI) is the most serious disease in this category)
- Heart failure
