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The page below is a sample from the LabCE course Body Fluid Differential Tutorial. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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The macrophages in this image have multiple large phagocytic vacuoles. This sample is a reactive pleural effusion in a patient with widely metastatic rhabdomyosarcoma.

These particular macrophages have been removing some of the red blood cells (RBCs) that have been released into the pleural space due to the spread of this patient's tumor. The bottom image is a phagocytic macrophage with ingested RBCs (erythrophage).