Unquestionably the medical laboratory plays an important role in the detection, diagnosis, and ultimately the treatment of medical disorders. As emphasized earlier in this program, the meticulous handling of patient samples from collection, preparation, and all the way through analysis is essential for accurate test results. Centrifugation is one of the most important steps in the preparation of clinical specimens for analysis. Consequently, it is paramount that those working in the medical laboratory not only have a basic knowledge in the theory of centrifugation but also be proficient in how to safely use and maintain centrifuges in their laboratory. The next two sections will focus on the steps necessary to safely use a centrifuge and how to keep it functioning properly.