Döhle bodies are seen in several conditions, including:
- infections
- burns
- leukemia
- chemotherapy
- inflammatory states
Döhle bodies are only present when the body is responding to unusually severe stress or stimulus. This severe stress may cause the cytoplasm of some cells to mature improperly.
Their presence does not aid in diagnosing the disorders in which they are found, but they are frequently seen along with toxic granulation and/or vacuoles in cases of infection or burns.
