Recognition and diagnosis of the inherited form of Pelger-Huet anomaly are essential because many of these Pelger-Huet neutrophils may be classified as bands; therefore, increased numbers of bands might be erroneously reported in these patients.
Since increased numbers of bands frequently indicate infection, reporting Pelger-Huet cells as standard band forms could result in inappropriate treatment for infection. Pelger-Huet cells have denser nuclear chromatin than neutrophilic band forms.
