It is important to recognize the presence of these morphological changes and to identify them for several reasons accurately:
- If the changes are pathological, their identification may aid the physician in diagnosing a specific condition.
- If the changes are not pathological, their identification alerts the physician to their presence, thus avoiding a possible misdiagnosis.
- If reactive, it indicates that although the cells function normally, they react to a stimulus. Indicating the presence of such cells may aid in determining the diagnosis or monitoring the course of the disease once a diagnosis has been made.