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The page below is a sample from the LabCE course Red Blood Cell (RBC) Morphology. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Prekeratocytes or Blister Cells

The red cell fragment in the center of this slide is sometimes referred to as a prekeratocyte or blister cell. Notice the cell appears to have a blister or pseudo-vacuole extending around the flat edge. This cell has freed itself from a fibrin strand, and when the vacuole bursts, one or more projections may be visible. Survival time in circulation for these cells is very short.