Hemoglobin Electrophoresis Patterns in Sickle Cell Disorders (Alkaline)

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The page below is a sample from the LabCE course Hemoglobinopathies: Hemoglobin S Disorders. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Hemoglobin Electrophoresis Patterns in Sickle Cell Disorders (Alkaline)

The following list corresponds to this image of an alkaline hemoglobin electrophoresis.

Lane 1: Control ASC
Lane 2: Control AF
Lanes 3 and 4 (patient 1): Homozygous sickle cell disease (Hb SS) Hb S is 100%
Lanes 5 and 6 (patient 2): Heterozygous sickle cell trait (Hb SA)
Lanes 7 and 8 (patient 3): Double heterozygous Hb SC disease (Hb SC)
Lanes 9 and 10 (patient 4): Sickle cell hemoglobin with hereditary persistence of fetal hemoglobin.