Graves' Disease

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The page below is a sample from the LabCE course Laboratory Assessment of Thyroid Function. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about Laboratory Assessment of Thyroid Function (online CE course)
Graves' Disease

  • Autoimmunity
    • Production of thyrotropin receptor antibody (TRAb) to block thyroid-stimulating hormone (TSH)
    • Production of Thyroid stimulating immunoglobulin (TSI) to stimulate thyroid hormone production
  • Leads to HYPERthyroidism
  • Exophthalmos (abnormal protrusion of eyeball(s)
  • Anxiety and nervousness
  • Pulmonary hypertension
  • Rapid heartbeat
  • Female to male ratio - 8:1
  • Approximately 0.5% of population
  • Likely under age 40 at diagnosis