The symptoms and clinical features of insufficient thyroid hormone production, or hypothyroidism, are considered generalized or non-specific when evaluated singly. However, when evaluated collectively, they present a picture that points to a root cause and the underlying condition. Those presenting with hypothyroidism will frequently present with an inability to lose weight, intolerance to cold temperatures, and chronically fatigued.
Low levels of thyroid hormones contribute directly to decreased and inefficient metabolism, leading to obesity and high blood pressure. Untreated hypothyroidism leads to cognitive impairment and depression.
Table 2 provides a summary of the more common symptoms and clinical features associated with hypothyroidism.
Table 2. Hypothyroidism Symptoms and Clinical Features.| Symptoms | Clinical Features |
| Fatigue | Obesity |
| Sensitivity to cold | Infertility |
| Constipation | Joint pain |
| Dry skin | High blood pressure |
| Unexplained weight gain | Heart disease |
| Puffy face | Depression |
| Hoarseness | Cognitive impairment |
| Muscle weakness | |
| Elevated cholesterol | |
| Joint pain and stiffness | |
| Heavy menstrual periods | |
| Thinning hair | |
| Impaired memory | |
| Swollen neck glands | |
