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The page below is a sample from the LabCE course Laboratory Assessment of Thyroid Function. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Thyroid Biochemistry: Summary

Iodine + tyrosine ---thyroperoxidase (TPO)---> monoiodotyrosine (MIT)
MIT + iodine -----TPO-------> diiodotyrosine (DIT)
2 DIT ------TPO------> thyroxine (T4)
T4 + selenium ----5DEO-----> triiodothyronine (T3) + iodine
The next pages will provide further details on the T4 and T3 hormones.