Clinical Relevance of D Phenotypes

How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 176 CE courses, most popular
$109Add to cart
Pick Your Courses
Up to 8 CE hours
$55Add to cart
Individual course$25Add to cart
Need multiple seats for your university or lab? Get a quote
The page below is a sample from the LabCE course Hemolytic Disease of the Fetus and Newborn. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about Hemolytic Disease of the Fetus and Newborn (online CE course)
Clinical Relevance of D Phenotypes

Clinically relevant information on D phenotypes can be summarized in Table 3.
Table 3. Clinical Relevance of D Phenotypes.
D phenotypeD antigen expressionRh(D) typingProduce anti-DRBCs to transfuseRhIG recommended**
D+Normal DAT No D+ or D- No
Weak DNormal but weak IAT NoD+ or D- No
Partial DAltered DAT* & IAT Yes D- Yes
Partial weak DAltered & variable DAT* & IAT Yes D- Yes
D-None IATYes D- Yes
*Depending on anti-D reagent used
**USA, UK, and parts of Canada