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The page below is a sample from the LabCE course ABO Typing Discrepancies. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Antigens and Antibodies

Simple Review of Antigens and Antibodies
Location Located in red cell Found in plasma
Binding Site Epitope Paratope
Solubility Insoluble Soluble

Antibody Isotypes (Classes)
IgG - ABO stimulated
IgM - ABO naturally occurring
The image to the right represents IgM. Notice its 10 antigen binding sites.