Antigens and Antibodies

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The page below is a sample from the LabCE course ABO Typing Discrepancies. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Antigens and Antibodies

Table 1. Simple Review of Antigen and Antibody Characteristics.
CharacteristicAntigenAntibody
LocationLocated in red cellFound in plasma
Binding SiteEpitopeParatope
SolubilityInsolubleSoluble
Antibody Classes (Isotypes)
IgA
IgD
IgE
IgG - ABO stimulated
IgM - ABO naturally occurring
The image to the right represents IgM. Notice its 10 antigen binding sites.