Segmented neutrophils are also referred to as segs, polymorphonuclear leukocytes, polys, and PMNs. Segmented neutrophils are the most mature neutrophilic granulocyte present in circulating blood. The diameter of a segmented neutrophil is approximately 9-15 microns, and the N:C ratio is approximately 1:3.
The cytoplasm of a segmented neutrophil resembles the cytoplasm of a band. It stains faintly pink and contains numerous fine specific granules, which stain pinkish-lilac with Wright or Giemsa stain.
A segmented neutrophil has the following characteristics:
- The nucleus is a deep purple, and the chromatin has a coarse, clumped texture.
- The nucleus has 2-5 lobes, with an average of 3.
- The lobes are connected by a fine filament or strand of the nuclear membrane.
- A filament is a thread-like strip so narrow that there is no visible nuclear material between the two sides.
