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The page below is a sample from the LabCE course Vitamin D. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Renal Disease

Those that may have kidney disease may not be able to convert 24-hydroxylase or 1-alpha-hydroxylase to 24,25-(OH)2D3 or to calcitriol (see the image below). This will impair vitamin D that is present from becoming biologically active, phosphorous levels are also elevated due to the renal disease and lack of excretion.