Breast Cancer Drugs
The aromatase inhibitors anastrozole (Arimidex), letrozole (Femara), and exemestane (Aromasin) are used in the treatment of breast cancer. They block estrogen production, which results in extremely low blood estrogen levels and bone loss. Some studies have also shown an increased risk of fractures, particularly at the spine and wrist.
Prostate Cancer Drugs Androgen deprivation therapy is a type of treatment for prostate cancer. Androgen deprivation therapy has been associated with reduced bone mineral density, which is greatest during the first year of therapy in men aged 50 years and older. This results in an increased risk of fractures.