Type 2 occurs in women or men older than 70 years of age and usually is associated with decreased bone formation along with the decreased ability of the kidney to produce 1,25(OH)2D3. The vitamin D deficiency results in decreased calcium absorption, which increases the PTH level and therefore bone resorption. In type 2 osteoporosis, cortical (outer surface of the bone) and trabecular (spongy) bone is lost, leading to an increased risk of hip, long bone, and vertebral fractures.
