Chromosome 11 Beta Thalassemia Intermedia B+/B+

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Chromosome 11 Beta Thalassemia Intermedia B+/B+

In Beta thalassemia intermedia, B+/B+, both beta chain loci show a partial deletion or inactivation of the gene.

Hemoglobin A is made to only 55% to 75% of its normal amount.

(drawing modified from Harmening, 1999)