Beta thalassemia major, B0/B0 (two gene mutations, deletions, or combination) results in very few to no beta chains being produced.
Hemoglobin A levels are at or near 0%.
Harmening, D. (2009). Clinical nematology and fundamentals of hemostatis. (5th ed.). FA Davis.Other genotypes of beta thalassemia major not depicted include B0/B+ (one beta chain deleted, one partially deleted) and B+/B+ (both beta chain genes partially deleted).
