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The page below is a sample from the LabCE course The Urine Microscopic: Microscopic Analysis of Urine Sediment. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Granular Casts

Granular casts are composed of cellular remnants and of by-products of protein degradation. Granular casts appear as irregularly-shaped cylinders of coarse or fine, highly refractive particles. A granular cast containing coarse brown granules is indicated by the yellow arrow in the image on the right (brightfield, 400X magnification).

The presence of an occasional granular cast is not considered pathologic.
Hyaline casts are also present in this field and are indicated by the blue arrows.