After the exposure, there is an incubation period that lasts 75 days on average, but it can vary from 30 to 180 days. Many individuals with acute HBV will have no symptoms at all. Some will have a mild illness with loss of appetite, nausea and vomiting, and fatigue. About 30% of infected individuals will develop clinical hepatitis with jaundice (yellow discoloration of the skin and eyes) due to liver dysfunction.