Coagulation Factors Monitored by the Prothrombin Time Test

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The page below is a sample from the LabCE course Detecting and Evaluating Coagulation Inhibitors and Factor Deficiencies. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Coagulation Factors Monitored by the Prothrombin Time Test

The Prothrombin Time (PT) test monitors the adequacy of the following factor levels:
Table 1. Extrinsic (and Common) Pathway.
FactorPathway
Factor I (Fibrinogen)Common
Factor II (Prothrombin)Common
Factor VCommon
Factor VIIExtrinsic
Factor XCommon
If one or more of the factors above are deficient, the PT test will be prolonged. This may indicate the need for a PT mixing study to determine the cause.