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The page below is a sample from the LabCE course Cerebrospinal Fluid. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Chemical Substances Present in CSF

The composition of CSF has some similarities to plasma; however, most analyte reference intervals are different for CSF than they are for plasma. For example, the protein level of normal CSF is dramatically lower than that of plasma.
Chemicals that are often evaluated in CSF samples include:
ChemicalCSF Reference Interval
120-132 mmol/L
15-45 mg/dL
40-70 mg/dL

Other chemicals that are also present in CSF include:
  • Calcium
  • Cholesterol
  • Creatinine
  • Lactic acid dehyrdogenase (LDH)
  • Phosphorus
  • Urea
  • Uric acid