Coarse Basophilic Stippling

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The page below is a sample from the LabCE course Erythrocyte Inclusions. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Coarse Basophilic Stippling

Coarse basophilic stippling is present in the cell in the center of the top slide image. The granules are larger and more prominent than those seen in fine stippling. Coarse basophilic stippling should be reported and can be clinically significant.
Another example of coarse basophilic stippling is seen in the bottom right image.