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The page below is a sample from the LabCE course Antibody Detection and Identification. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Rule-Out Procedure Summary Guidelines

These guidelines should be followed when performing initial rule-out procedures:

  • Only cells that did NOT react can be used to rule-out.
  • For antibodies that exhibit dosage, homozygous cells are preferred for rule-out.
  • Rule-out is not free of error and should be evaluated in the context of other data, such as the phase of testing.