Picking Selected Panel Cells Conservatively

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The page below is a sample from the LabCE course Antibody Detection and Identification. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about Antibody Detection and Identification (online CE course)
Picking Selected Panel Cells Conservatively

Choose cells that can help rule out more than one antibody at a time in order to help decrease supply usage and tech prep time.
Example: Ruling out Anti-C, -Fyb, and -M if you have a suspected Anti-Jka
CcFyaFybJkaJkbMN
Panel cell 9+00+0++0
Panel cell 10+0++0+0+
Panel cell 11++0+0++0
Panel cell 12++++0++0
Instead of running 3 separate cells to rule out the antibodies, you can choose one that is homozygous positive for M, C, Fyb and negative for Jka. Panel cell 9 works in this case.
If the only antibody that is present is Anti-Jka, then your test results should be negative. If the results are positive then further rule outs will be needed to determine what is present.