Predisposing factors to MRSA infection
Prior antibiotic therapy and prolonged hospital stay have been found to be the prime conditions predisposing to infections with MRSA. The differences in outcome for patients infected with MRSA do not differ significantly from those infected with methicillin (oxacillin)-sensitive strains.
Decreasing the risk of MRSA colonization
Host protein domains that are complementary to staphylococcal surface epitopes have been shown as the cause for colonization. To decrease the risk of staphylococcal colonization of indwelling catheters in the future, the development of specific inhibitors can potentially reduce this chance of colonization. This is particularly true when early removal of the catheter is not an option in certain cases.
