Location, Structure, and Normal Function of the Pituitary Gland

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Location, Structure, and Normal Function of the Pituitary Gland

The pituitary gland known as the master gland, or hypophysis, is located in the midbrain. It contributes to the regulation of many functions of the body including blood pressure, blood sugar levels, reproductive organs, water retention, metabolism, lactation, and growth.
The pituitary gland has three regions: anterior, intermediate, and posterior.
The anterior pituitary produces a variety of hormones with varied functionality. The hormones of the anterior pituitary include follicle-stimulating hormone (FSH), luteinizing hormone (LH), adrenocorticotropic hormone (ACTH), thyroid-stimulating hormone (TSH), prolactin, endorphins, and growth hormone (GH).
The posterior pituitary secretes antidiuretic hormone (ADH), also known as vasopressin, and oxytocin, which are produced in the hypothalamus.
The intermediate pituitary is the site of melanin production from melanocytes.
Table 3 summarizes the various pituitary hormones, their location in the pituitary, and their function.
Table 3. Pituitary Hormones.
Hormone NamePituitary LobeHormone TypeFunction
FSH Anterior PolypeptideGamete production
LH Anterior PolypeptideOvulation and sex hormone/androgen release
ACTH AnteriorAmino AcidRelease hormones from adrenal cortex
TSH Anterior PolypeptideStimulate thyroid hormones (T3 and T4)
Prolactin AnteriorAmino AcidLactation in mammary glands
GHAnterior PolypeptideGrowth of cells, tissues, and bones
ADHPosteriorAmino AcidRetain water
OxytocinPosteriorAmino AcidStimulate uterus/ contractions during birthing
MelaninIntermediateAmino AcidPigmentation production